The Bayer company's Alka-Seltzer brand pain-reliever and antacid boasts speedy relief—and one of the most notable advertising (see entry under 1920s—Commerce in volume 2) campaigns in history. Alka-Seltzer was introduced in 1931 by Miles Laboratories (purchased by Bayer in 1979). The product was originally used by some consumers as a remedy for hangovers. Alka-Seltzer's effervescent (fizzing) tablets release their active ingredients when dissolved in water. Each Alka-Seltzer tablet, which comes in origianl, lemon-lime, and cherry flavors, contains 1,916 milligrams of sodium bicarbonate, 1,000 milligrams of citric acid, and 325 milligrams of aspirin. Bayer also manufactures a range of variations on the basic product, including chewable Alka Mints and Alka-Seltzer PM for nighttime relief.

Alka-Seltzer advertisements are considered classics. From 1954 to 1964, its broadcast commercials featured a cheerful animated character named "Speedy Alka-Seltzer," whose voice was supplied by voice-over actor Dick Beals (1927–), and a demonstration of two tablets fizzing after being dropped into a...