The skeleton serves number of functions in vertebrates
Just to expand and give examples of the previous entry.
Bones have eleven main functions:
· Protection — Bones can serve to protect internal organs, such as the skull protecting the brain or the ribs protecting the heart and lungs.
· Shape — Bones provide a frame to keep the body supported.
· Movement — Bones, skeletal muscles, tendons, ligaments and joints function together to generate and transfer forces so that individual body parts or the whole body can be manipulated in three-dimensional space. The interaction between bone and muscle is studied in biomechanics.
· Sound transduction — Bones are important in the mechanical aspect of overshadowed hearing.
· Blood production — The marrow, located within the medullary cavity of long bones and interstices of cancellous bone, produces blood cells in a process called haematopoiesis.
· Mineral storage — Bones act as reserves of minerals important for the body, most notably calcium and phosphorus.
· Growth factor storage — Mineralized bone matrix stores important growth factors such as insulin-like growth factors, transforming growth factor, bone morphogenetic proteins and others.
· Fat Storage — The yellow bone marrow acts as a storage reserve of fatty acids
· Acid-base balance — Bone buffers the blood against excessive pH changes by absorbing or releasing alkaline salts.
· Detoxification — Bone tissues can also store heavy metals and other foreign elements, removing them from the blood and reducing their effects on other tissues. These can later be gradually released for excretion.
· Endocrine organ - Bone controls phosphate metabolism by releasing fibroblast growth factor - 23 (FGF-23), which acts on kidney to reduce phosphate reabsorption.