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The nastiest gene of all? (multiple tumor suppressor 1)

About 2 pages (514 words)

The Economist (US), July 2nd, 1994

Researchers disagree about the carcinogenicity of the multiple tumor suppressor 1 (MTS1) gene. One research team found the gene in almost half of tumor cells raised in the laboratory, but other researchers have found MTS1 much less often in tumor cells taken from patients.

GIVEN that bad genes cause cancer, there is a certain kudos in finding the worst of them all. The ras gene is impressively widespread. So are mutant genes for p53, a protein which is meant to suppress tumours and which, when it fails, allows them to spread. In April, scientists at Myriad Genetics in Salt Lake City and at th...

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