Bioscience Technology, June 1st, 2005
The importance of transcriptional regulation, coupled with the fact that transcription factors are influenced by a variety of stimuli and can be modulated through several different biochemical modifications, suggest that intervention at the point of transcription is a promising strategy for the development of targeted therapeutics.
Because proteins perform the vast majority of cellular functions, it is critical for cells to regulate protein levels precisely. While gene expression is a multi-step process in which DNA information is copied first into RNA (transcription) and then translated in...
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