Chemistry and Industry, June 5th, 1995
Polyketides are naturally-occurring compounds, most often produced by microorganisms such as fungi and the filamentous bacteria (the actinomycetes). The route by which these compounds are formed is one of the most widespread in Nature.[1] It is responsible for a vast array of natural products (see Figure 1) with structures varying from simple aromatic compounds like 6-methylsalicylic acid (6-MSA) to the gigantic polycyclic ether maitotoxin, whose molecular weight of 3422Da makes it the largest known secondary metabolite.[2] Apart from microorganisms, polyketides are also isolated from a wide...
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