Biopharm, December 1st, 2001
Nuclear magnetic resonance (NMR) spectroscopy specifically probes the local environment around the nucleus of each atom in a molecule. The spectrum thus generated is a unique chemical signature of the molecule.
How NMR Works
NMR is ubiquitous in modern analytical chemistry. In a magnetic field, atomic nuclei with magnetic moments (most of the periodic table) acquire a magnetization parallel to the field. A burst of energy at the right frequency, in the FM radio frequency range, can perturb that magnetization. Magnetization then precesses around the magnetic field, giving rise to a voltage th...
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