Science News, March 26th, 1994
The body depends on a few types of large proteins to determine whether substances are friend or foe. These proteins get their names from the genes that code for them - the major histocompatibility complex (MHC).
Last year, several research groups figured out how one class of these molecules, known as MHC-I proteins, binds to small pieces of protein and presents those pieces, called peptides, to the body's immune system (SN: 1/30/93, p.72).
On the basis of X-ray crystallographic data, researchers have now created this computer graphic. It snows that another type of MHC molecule, MHC-II, doe...
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