The Biological Bulletin, October 1st, 2004
It has been suggested that [Ca.sup.2+] events occuring during the blastula period of zebrafish development might be involved in mediating the cell-to-cell adhesion between the enveloping layer (EVL) cells and/or might somehow play a role in dorsoventral patterning of the embryo. Using the [Ca.sup.2+]-sensitive luminescent reporter, aequorin, and a custom-designed photon imaging microscope (PIM), we have started to re-investigate the patterns and possible functions of the blastula period [Ca.sup.2+] transients. We have demonstrated that distinct [Ca.sup.2+] transients occur throughout this pe...
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