Plant Physiology, May 1st, 2002
Gene function is subjected to the effects of surrounding chromatin. The nature of these effects may be epigenetic occurring in some cells, but not others, of the same genetic background. Epigenetic regulatory mechanisms remain an enigma, but recent studies have provided informative insights into the molecular basis underlying them (for review, see Henikoff et al., 2001; Martienssen and Colot, 2001; Reik et al., 2001).
Inside the nucleus, the three levels of structural compaction of DNA are seen as 11-, 30-, and 300-nm fibers, the latter representing the folding of the 30-nm chromatin fiber in...
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