Indian Journal of Dermatology, Venereology and Leprology, January 1st, 2008
Sir,
Hereditary leiomyomatosis with renal cell carcinoma (HLRCC) is a rare syndrome of cutaneous leiomyoma, uterine leiomyomatosis and renal cell carcinoma. [1 ] It is an autosomal dominant disorder caused by mutations in the gene encoding the enzyme fumarate hydratase (FH). Launonen et al., [1 ] identified that the predisposition gene 'HLRCC' is mapped to 1q42-q44. It is often an unrecognized tumor syndrome. Its awareness is important because of its association with aggressive uterine fibroids and renal cell cancer. We report a case with multiple cutaneous leiomyomas and papillary renal cell...
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