Clinical Chemistry, June 1st, 2006
C-94
C. Rohlfing, S. Connolly, J. England, R. Little. University of Missouri, Columbia, MO.
Elevated fetal hemoglobin (HbF) levels have been reported to interfere with some assays that measure glyeated hemoglobin (GHb, reported as hemoglobin A1c or HbA1c), an important measure of glyeemia in patients with diabetes mellitus. Previous studies have shown significant diserepaneies between HbA1c results measured by different routine methods in patients with elevated HbF levels. The IFCC has developed a definitive reference method for the measurement of HbAIc which utilizes enzymatie digestion to ...
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