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Diazepam replacement

About 3 pages (763 words)

Military Medicine, August 1st, 2000

Dear Editor:

We are writing in response to the letter of November 11, 1999 by Major Harris and Captain Gausman, published in the February 2000 issue, in which they advocate the replacement of diazepam with lorazepam as the field anticonvulsant treatment for nerve agent-induced seizures.

The authors are correct to point out that soldiers pretreated with pyridostigmine are much more likely to go into prolonged status epilepticus when exposed subsequently to nerve agents and promptly treated with atropine and 2-PAM CI (MARK 1), rather than die, than are soldiers not so pretreated. Work at the U...

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