The Scientist, January 17th, 2005
| TOOLS & TECH | Army-based techniques highlight chromosomal variations at the molecular level
For decades, cytogeneticists have pored over images of metaphase chromosomes from tumors, noting the many gross aberrations these karyotypes can reveal. As classical techniques give way to fluorescence in situ hybridization (FISH), identifying genes affected in these chromosomal aberrations will likely offer clues to tumor progression.
Now, FISH and other relatively labor-intensive visual techniques are beginning to give way to newer, microarray-based methods. Of these, the best known is array-...
HighBeam Research, Free Preview: 'Cytogeneticists Embrace Molecular Karyotyping'... Full Membership required for unlimited access. Free 7-day trial.
Subscribers: HighBeam content is only available to HighBeam subscribers. Click the link above for more information.
