Science News, August 5th, 1989
Cutting away DNA the mitochondrial way
When British researchers last year showed that a deletion of DNA within the mitochondria of cells caused a series of related muscle ailments, they revealed a new type of disease-causing genetic defect. Now a team at Emory University in Atlanta suggests it has unraveled the basic mechanism causing the loss of mitochondrial DNA.
"We think we understand how the deletions occur, that the deletions are a direct result of the normal replication process and that the deletion process can occur anytime during [fetal] development," team leader Douglas C. Wallac...
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