The Hastings Center Report, November 1st, 1999
Imagine a moment in the (possibly not too distant) future, when xenotransplantation is considered clinically feasible. Animal studies--say, transplantation of pig kidneys into baboons--have been "successful," with survival of six to twelve months at a clinically acceptable level of immunosuppression. Genetic engineering has succeeded in creating a lineage of pigs whose endothelial cells do not contain the glycoproteins that would trigger hyperacute rejection. Systematic human trials are now proposed--protocols for both kidney and heart transplants are being developed. Faced with the real prosp...
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