The Scientist, March 14th, 2005
| HOT PAPERS | DJ-1 spurs a rethink on neurodegenerative mechanisms
The discovery of several genes linked to Parkinson disease (PD) in recent years has spawned extensive research efforts to elucidate the underlying mechanism of this prevalent neurological disorder. This issue's hot Paper focuses on the discovery of a third gene, DJ-1, which is mutated in a small subset of patients with PD.1 Neurologist and geneticist Vincenzo Bonifati, along with molecular biologists Ben Oostra and Peter Heutink and colleagues at Erasmus University Medical Center in Rotterdam, showed that DJ-1 mutations are i...
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