Kill Bill v2 opens with Chapter 6 in which The Bride (a.k.a Black Mamba, a.k.a Mommy, a.k.a Beatrix Kiddo) lying on the floor. Covered in blood, she tells Bill that the baby she was carrying was his just as he attempted to kill her by shooting her in the head.

The scene then cuts to The Bride driving on her way to see and kill Bill. We are reminded that she was in a coma for five years and has vowed to kill all members of her former death squad and then Bill. After successfully killing two former colleagues of the "Deadly Viper Assassination Squad" (a.k.a DiVAS) namely, Vernita Green (played by Vivica Fox) and O-Ren Ishii (played by Lucy Liu) in Kill Bill v1, The Bride has two more obstacles on her way to killing Bill...