(born April 26, 1573, Florence—died July 3, 1642, Cologne) Queen consort of Henry IV of France. The daughter of Francesco de' Medici, of the noted Medici family, she was married in 1600 to Henry as his second wife. On his assassination in 1610, she became regent for their son, Louis XIII. Guided by the unscrupulous marquess d'Ancre, she squandered state revenues and bought the loyalty of rebellious nobles.
After Ancre was assassinated, Louis assumed the throne (1617) and exiled Marie to Blois. She tried to raise a revolt and won favourable peace terms through her adviser, the future cardinal de Richelieu. Restored to the king's council (1622), she obtained a cardinal's hat for Richelieu and persuaded Louis to make him chief minister. Richelieu gradually withdrew from Marie's influence and by 1628 was opposing her policies. She attempted to have him dismissed, but Louis rejected her plot and banished Marie from court. In 1631 she fled to Brussels, where she later died in poverty.
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