Wormwood, a character in C. S. Lewis' The Screwtape Letters

Wormwood (star), a star that falls onto Earth poisoning the freshwater sources of water in the Book of Revelation of the Christian Bible

"Wormwood," a song by Tristania

"Wormwood," a song by Snowman

Wormwood: Curious Stories from the Bible, an album by The Residents

Wormwood (G.P.Taylor), a fantasy novel by Graham Taylor

Wormwood: A Drama of Paris, a novel by Marie Corelli

Wormwood (album), an album by moe.

Wormwood (book), a series of short horror stories by Poppy Z. Brite

Wormwood (journal), a journal of literature and literary criticism

"Wormwood," a song by Callisto

Wormwood (computer virus), a computer virus written for FreeBSD

Wormwood: Gentleman Corpse, a comic book series by Ben Templesmith from IDW Publishing

Various plants of the genus Artemisia, but commonly Absinth Wormwood