George Whipple (1878–1976), American physician, biomedical researcher, Nobel Prize winner

Edwin Percy Whipple (1819–1886), American essayist and critic

Henry Benjamin Whipple (1822–1901), first Episcopal bishop of Minnesota, U.S.A.

Abraham Whipple (1733–1819), American revolutionary naval commander

Diane Whipple (1968–2001), fatal victim of a dog attack in San Francisco

Whipple Van Ness Jones, skier

Whipple procedure, surgical removal of pancreatic cancer (devised by Allen Whipple)

Whipple's disease, a rare bacterial disease (first described by George Whipple)

Fort Whipple, fort established in 1863 in Arizona Territory near Prescott (after Amiel Weeks Whipple)

Mr. Whipple, fictional character in American television ads for Charmin toilet paper

Whipple Mountains, mountain range in southeastern California, U.S.A

Whipple's index, measure used in demography (study of human population dynamics)

Fred Lawrence Whipple (1906–2004), American astronomer

William Whipple (1730–1785), signer of the United States Declaration of Independence as a representative of New Hampshire

John Adams Whipple (1822–1891), American inventor and early photographer

Whipple's triad, conditions necessary for proving a diagnosis of hypoglycemia (by Allen Whipple)

Frances Harriet Whipple Green McDougall, born Frances Harriet Whipple (1805–1878), abolitionist, poet, novelist, editor, botanist, spiritualist medium, and advocate of women's, voters', and workers' rights

Amiel Weeks Whipple (1816–1863), American military engineer and surveyor

Prince Whipple, eighteenth century African, participant in American Revolution

Fred Lawrence Whipple Observatory, astronomical observatory in Arizona, U.S.A.

Walter Whipple, Associate Teaching Professor of Polish, author of many English translations of Polish poetry

Mary Margaret Whipple (1940– ), Virginia politician

Whipple Museum of the History of Science, science museum of the University of Cambridge

Whipple shield, meteor shield for spacecraft invented by Fred Whipple

Allen Whipple (1881–1963), American surgeon, eponym of the Whipple procedure and Whipple's triad

USS Whipple, designation of three U.S. Navy ships (after Abraham Whipple)

36P/Whipple, periodic comet discovered by Fred Whipple

Francis John Welsh Whipple (1876–1943), British mathematician and meteorologist

Triple Whipple Truss, bridge design used in the 1800s