Villanueva del Río Segura, a municipality in the Region of Murcia, Spain

Eddie Villanueva (Eduardo Villanueva) (1946- ), a religious and political figure in the Philippines

Villanueva, Zacatecas, a town in Zacatecas state, Mexico

Charlie Villanueva (1984- ), a Dominican-American basketball player for the NBA

Enrico Villanueva, a Filipino professional basketball player in the Philippines

Rene Villanueva (1954- ), a Filipino author published in the Philippines

Villanueva de la Cañada, a municipality in the Community of Madrid

James Villanueva, a professor of English from Singapore

Carlos Villanueva (1983- ), a Dominican professional baseball player in USA

Juan de Villanueva (1739-1811), a Spanish neoclassical architect

Villanueva State Park, a New Mexico State Park

Villanueva de la Fuente, a small village in the Castilla-La Mancha region

Sal Villanueva, an American record producer (1999-2007)

Armando Villanueva (1915- ), Peruvian politician, full name Armando Villanueva del Campo

Villanueva de Córdoba, a municipality in Andalusia

Alejandro Villanueva (1908-1944), a Peruvian football (soccer) player in Peru

Miguel Villanueva (1990- ), a professional swimmer from the Philippines

Villanueva, Santander, a town and municipality in Santander Department

Club Deportivo Villanueva, a football (soccer) team in Villanueva de Córdoba

Sergio Villanueva Fernández, Spanish footballer

Villanueva, Bolívar, a town and municipality in Bolívar Department

Villanueva, La Guajira, a town and municipality in La Guajira Department

Villanueva, Misamis Oriental, a municipality in Misamis Oriental province

Villanueva, Casanare, a town and municipality in Casanare Department

José Villanueva, an amateur boxer from the Philippines

Enrique Villanueva, Siquijor, a municipality in Siquijor province

Danny Villanueva (1937- ), an American football kicker for the NFL

Villanueva, New Mexico, a village in New Mexico, USA

Héctor Villanueva (1964- ), a Puerto Rician professional baseball player in USA

Villanueva FC, a football (soccer) team in Villanueva, Cortés

Anthony Villanueva , a Filipino boxer, represented Philippines in Olympics

Rafael Villanueva, a Dominican classical musician

Villanueva de los Infantes, a municipality in Ciudad Real, Castile-La Mancha region

Villanueva, Cortés, a municipality in Cortés department, Honduras