Vector Meson Dominance, in physics a model describing the hadron photoproduction process.

Visual molecular dynamics, a molecular modelling and visualization computer program

Versatile Multilayer Disc, a high-capacity optical disc technology designed for High Definition Television

the academic degree bestowed upon a Veterinary Medical Doctor or (colloquially) a Veterinarian by a University —e.g. 'Jane Smith, VMD.'

The VMD degree (Veterinariae Medicinae Doctoris) is the equivalent of the DVM degree (Doctor of Veterinary Medicine), but indicates that the degree was earned at the University of Pennsylvania School of Veterinary Medicine, in Philadelphia, PA. It is the only veterinary school that bestows the VMD degree.

Sierra Video and Music Data File, a Full-motion video format used in Sierra games such as Phantasmagoria and Gabriel Knight 2.