Uncle Tom's Cabin is an anti-slavery novel by American author Harriet Beecher Stowe. Uncle Tom's Cabin may also refer to:

Tom Shows, stage productions based on Uncle Tom's Cabin

Uncle Tom's Cabin (film), one of the film versions of the novel

Uncle Tom's Cabin (album), the proposed title of the Warrant album Cherry Pie, and a song from the album

A Key to Uncle Tom's Cabin by Harriet Beecher Stowe, written to document the sources of her anti-slavery novel

Onkel Toms Hütte (Berlin U-Bahn), a Berlin U-Bahn station named after Uncle Tom's Cabin