Ulysses S. Grant, former U.S. General and 18th President of the United States

United States Government, or Federal government of the United States

Unix Support Group, an AT&T group that commercialized a series of Unix computer operating system versions

Urine Specific Gravity (kidney), a measure of urine concentration or relative density

University Student Government, a part of a students' union

Medical ultrasonography, an ultrasound-based diagnostic imaging technique used to visualize internal organs

USG Corporation, an American construction materials manufacturer

Under-Secretary-General of the United Nations

University System of Georgia, the organizational body that includes all public institutions of higher learning in Georgia, United States

USG people, a European HR/staffing/temporary employment organization based in The Netherlands. It is a merger (and three letter acronym) of Unique, Start and Goudsmit.

Universities at Shady Grove, an educational facility in Rockville, Maryland, United States