United States Constitution, the supreme law of the United States of America

United States Congress, the legislative branch of the federal government of the United States

University of Southern California (Los Angeles, California, USA)

Upper St. Clair High School (Upper St. Clair, Pennsylvania, USA)

University of South Carolina (Columbia, South Carolina, USA)

United Nations Security Council, an organ of the United Nations

United States Constabulary, the security force of the U.S. Occupation Zone of West Germany

United States Code, a compilation and codification of the general and permanent federal Law of the United States

University of Santiago de Compostela (Santiago de Compostela, Spain)

University of San Carlos (Cebu City, Philippines)

Ulster Special Constabulary, a former reserve police force in Northern Ireland

a former acronym for the University of Southern Colorado, renamed in 2003 to Colorado State University-Pueblo

United Somali Congress

WWE United States Championship, defended in World Wrestling Entertainment

University of the Sunshine Coast (Queensland, Australia)

University Senior College, a year eleven and twelve school in Adelaide, South Australia

United Services College (Westward Ho!, Devon, England)

Ultimate Street Car, largest modified car festival in the UK

Heckler & Koch Universal Self-Loading Carbine, a firearm

University of the Sacred Heart (Puerto Rico) or Universidad del Sagrado Corazón (San Juan, Puerto Rico)