U.S. Open (golf), golf tournament of the United States Golf Association

U.S. Open (taekwondo) Taekwondo tournament of the United States Taekwondo governing body

US Open (tennis), fourth event of the Grand Slam tournaments

U.S. Open Chess Championship

U.S. Women's Open (golf), golf tournament of the LPGA

U.S. Open 9-ball

U.S. Open (darts)

U.S. Open (squash)

U.S. Open (go)

U.S. Open (bowling)

U.S. Open (cycling)

U.S. Open (crosswords), former crossword-solving tournament

U.S. Open Badminton Championships, badminton tournament

Lamar Hunt U.S. Open Cup, soccer tournament held between American soccer clubs from the MLS and the minor leagues