Tom Thumb (boat), a boat used by Matthew Flinders in 1796.

Tom Thumb, a traditional hero in English folklore

General Tom Thumb, the stage name of Charles Sherwood Stratton (1838–1883)

Tom Thumb Food & Pharmacy, a grocer in the Dallas, Texas area of the U.S.

Thumbling, the "Tom Thumb" in Grimm's Fairy Tales

Tom Thumb, a young elephant who the elephant Jumbo allegedly died trying to save.

Tom Thumb (locomotive), the first American-built steam locomotive

tom thumb (1958), a feature film directed by George Pal; cast included Peter Sellers

Tom Thumb (comics), the codename of two Marvel Comics superheroes

"Just Like Tom Thumb's Blues" is a song written by Bob Dylan, released on his 1965 album Highway 61 Revisited.