a 1922 book of detective stories by G. K. Chesterton

two suspense films directed by Alfred Hitchcock:

, a book by David Leavitt

The Man Who Knew Too Much (1956 film), starring James Stewart and Doris Day

The Man Who Knew Too Much (1934 film), starring Leslie Banks and Edna Best

"The Man Who Knew Too Much" (article), an influential article by Marie Brenner for Vanity Fair on tobacco industry whistle-blower Jeffrey Wigand which formed the basis of the film The Insider

"The Man That Knew Too Much", a song by silverchair from their Young Modern album