The Human Factor (film), a 1979 film based on Greene's novel, directed by Otto Preminger

The Human Factor is a 1978 novel by Graham Greene, and it may also refer to:

Human factors, a concept related to ergonomics

"The Human Factor" (1963 The Outer Limits), a 1963 episode of The Outer Limits

"The Human Factor" (2002 The Outer Limits), a 2002 remake of the 1963 episode, as part of the revived version of The Outer Limits

The Human Factor (Doctor Who audio), an audio drama based on the British TV series Doctor Who

The Human Factor (album), a 1991 album by Metal Church

The Human Factor (book), a 2004 nonfiction book by Kim Vicente