Standoff (TV series), a canceled FOX television series.

Standoff (separator), used in mechanics and electronics to separate two parts from one another.

A social confrontation or conflict, such as an impasse, stalemate, or Mexican standoff.

Standoff distance, a certain safety distance away from a hazard or objective (live bomb, fire, artillery aimpoint, etc.) that is mandated by some kind of standard operating procedure.