Sprague is the name of several places in North America:

L. Sprague de Camp, author

Frank J. Sprague, Father of Electric Traction

Clifton Sprague, American admiral during World War II

Charles A. Sprague, former Governor of Oregon

William Sprague (1830-1915), a politician from Rhode Island, nephew of William Sprague (1799-1856)

Jack Sprague, the only 3-time NASCAR Craftsman Truck Series Champion

Ken Sprague, political cartoonist

Sprague, Alabama, Montgomery County, Alabama

Sprague, Connecticut

Ed Sprague (third baseman), former Major League Baseball third baseman, and son of the pitcher

Sprague Cleghorn, former NHL hockey player

Charles Sprague (poet), American poet

William Sprague (1799-1856), a politician from Rhode Island, uncle of William Sprague (1830-1915)

W.G.R. Sprague, London Theatre designer

Sprague, Washington

Sprague, Nebraska

Peleg Sprague, politician from the state of Maine

Isaac Sprague, botanical illustrator

Erik Sprague, the self-styled Lizardman

Ed Sprague (pitcher), former Major League Baseball pitcher

William Sprague (1809-1868), a politician from Michigan

Sprague Brothers, a rock band from Wichita Falls, Texas

Lucian Sprague, American railroad executive

Charles E. Sprague, accountant, civil war hero, Volapükist, spelling reformer

A number of prominent people named Charles Sprague

Peleg Sprague (New Hampshire), politician from the state of New Hampshire

The Sprague River in southwestern Oregon

William Sprague (1609–1675), original American settler

Isaac W. Sprague, the Original Thin Man

A number of prominent politicians named William Sprague

Charlie Sprague, an American baseball player

Sprague Field, a multi-purpose stadium on the campus of Montclair State University in New Jersey

Royal Sprague, 11th Chief Justice of the Supreme Court of California

Sprague-Grundy theorem, a theorem in recreational mathematics