Supermarine Spitfire, a British single-seat fighter aircraft used in World War II

Spitfire Pistol, a British-made 9 mm semi-automatic pistol

Windsor Spitfires, a junior ice hockey team in the Ontario Hockey League

Triumph Spitfire, a small two-seat British sports car from Triumph Motor Company

Fictional future creatures in the TV show The Future Is Wild:

Spitfire (1994 film), a U.S. film starring Lance Henriksen

Lupe Vélez, an actress known as "the Mexican spitfire"

The Mexican Spitfires Sydney-based Australian indie-pop band of the 1980s; sometimes abbreviated as "the Spitfires" or "the Spitties"

Spitfire (Russian band), a ska band from Saint Petersburg, Russia

Spitfire, the U.S. title of the 1942 British film The First of the Few

Spitfire (US band), a hardcore band from Virginia Beach, Virginia, USA

Spitfire (song), by Norwegian psyco-pop artist Bertine Zetlitz (2000)

Spitfire (New Universe), a.k.a. Spitfire and the Troubleshooters and Codename: Spitfire, a comic book published under the New Universe imprint of Marvel Comics

Spitfire (comics), a fictional character in Marvel Comics World War Two-era superteam "The Invaders"

Spitfire Wheels, a skateboard-wheel brand by Deluxe Distribution

Spitfire (UK band), a garage rock band from Crawley, West Sussex, England

Spitfire (BBS), a software program for operating a Bulletin Board System

Spitfire (beer), a UK bottled and cask beer

Spitfire sawfly, a type of insect and its caterpillar found in Australia

Spitfire (Jefferson Starship album), a 1976 album by Jefferson Starship

Spitfire Records, a heavy metal-oriented record label

Spitfire (1934 film), a U.S. film starring Katharine Hepburn

Spitfire Security Server, an enterprise information security product manufactured by Bloombase Technologies

HMS Spitfire, the name of three British naval ships

USS Spitfire, the name of four U.S. naval ships