Southwest Airlines, a domestic United States airline

South West Trains, a UK train operating company

Southwestern Art is a style of art prevalent in the desert Southwest of the United States, particularly centered in Santa Fe, New Mexico

Southwestern University, a private university located in Georgetown, Texas

Southwestern University School of Law, one of the oldest law schools in California

Southwest Conference, the NCAA college football conference

Southwestern Company, an American direct-selling book publisher

UT Southwestern Medical School, a prestigious medical school located in Dallas, Texas

Southwest High School (Minneapolis, Minnesota)

Washington, D.C. (southwest)

Southwestern Baptist Theological Seminary, a Baptist school in Fort Worth, Texas

Southwest Golf Classic, a former PGA Tour golf event

The Southwestern United States

Southwest China

Southwestern blot

Southwest Province, Cameroon

South West (Western Australia)

Southwest or south west is the ordinal direction halfway between south and west, the opposite of northeast. Southwest or south west may also refer to:

The South west Biosphere Reserve in Australia; see List of Biosphere Reserves in Australia

South West England, principally the counties of Dorset, Somerset, Devon and Cornwall