Slick Willie, a derogatory nickname used by some critics of President Bill Clinton

Slick (Experiment 020), an experiment from Lilo & Stitch

Military slang for a helicopter, usually used when referring to the UH-1 "Huey"

Slick (magazine), upmarket magazines printed on coated (slick) paper, as opposed to pulp magazines

Slick, one of the main characters in the webcomic Sinfest

Grace Slick, singer

Slick, the final boss in the video game River City Ransom

Slick Rick, a rapper

Slick tire, used in motor racing

Ricky Bell (singer), a.k.a. Slick, R&B singer for New Edition & Bell Biv DeVoe

Ken Johnson (wrestling), a.k.a. Slick, former WWE Manager

Slick, Oklahoma

Slick (tool), a large woodworking chisel

A puddle, especially of oil, as in an oil spill