22815 Sewell, an asteroid un the Solar System

Anna Sewell (1820–1878), British writer, author of Black Beauty, daughter of Mary Wright Sewell

Sewell's Point, Norfolk, Virginia, United States

Anthony Sewell (b. 1962), American Bicycle Motocross racer

Sewell, New Jersey

Sewell, Bedfordshire

Luke Sewell (1901–1987), American baseball player and manager, brother of Joe Sewell

William Joyce Sewell (1835–1901), US Senator from New Jersey

John Sewell, Mayor of Toronto

Brian Sewell, English art critic

Henry Sewell (1807–1879), first prime minister of New Zealand, brother of James Edwards Sewell and William Sewell

Rufus Sewell (b. 1967), English actor

Joe Sewell (1898–1990), American baseball player, brother of Luke Sewell

Sewel motion, a procedure of the Scottish Parliament

George Sewell (b. 1924), English actor

John Sewell (footballer), English footballer who played during the 1970s

Geoff Sewell, New Zealand tenor

Brocard Sewell (1912–2000), British monk and literary figure

Elyse Sewell (b. 1982), American fashion model

William Sewell (1804–1874), English author, brother of James Edwards Sewell and Henry Sewell

Edward Granville Sewell, American mathematician and ID proponent

Sicily Sewell, (b. 1983), American actress

Sewell, Chile

William H. Sewell (1909–2001), Sociology professor and chancellor of UW-Madison

Cecil Harold Sewell, British Army lieutenant, recipient of the Victoria Cross during World War I

John Sewell (Miami), third Mayor of Miami, Florida

James Edwards Sewell (1810–1903), warden of New College, Oxford, brother of Henry Sewell and William Sewell

John Sewel, member of the British House of Lords

Gillian Sewell (b. 1972), Canadian field hockey player

Robert Sewell (1845–1925), British civil servant in India and Indian historian

James Witt Sewell (1865–1955), British author and professor of English

Mary Wright Sewell, British children's author and mother of Anna Sewell

Harold Sewell, British Olympic athlete