Set point (electronics), a term which refers to the point at which an electrical circuit is either activated or de-activated

SetPoint (software) is the name of the driver suite for Logitech mice

Setpoint (control system) is the target value that an automatic control system, for example PID controller, will aim to reach.

Set point (tennis), a tennis term meaning one player is one point away from winning a set

Set point (medicine), a term referring to any one of a number of quantities (e.g. body weight, body temperature) which the body tries to keep at a particular value (see also homeostasis)