SPb is also frequently used by Russians in reference to Saint Petersburg.

Sripathi Panditaradhyula Balasubramanyam, a prolific singer from Nellore, Andhra Pradesh, India

Simple Payback (SPB) -- an engineering economics measure

Spindle pole body, the functional equivalent of the mammalian centriole in yeast

Scappoose Industrial Airpark, (IATA: SPB, ICAO: KSPB)

Seaplane base, a landing area for seaplanes (abbreviation used by the FAA and others).

Schynige Platte Bahn, a mountain railway in the Bernese Oberland, Switzerland

Belarus Free Trade Union (SPB) - a trade union in Belarus.