Software engineering

Sex education

Selenium, chemical element

Stock exchange

Schloss Einstein, a German (famous) television program for children and teenagers

Systems Engineering

Scottish Executive, the Scottish Government, the executive arm of the Scottish Parliament; and the civil service serving that government

Societas Europaea, European public company, see European Company Statute

Sony Ericsson, a mobile phone company formed by Sony and Ericsson

Square Enix, a video game company

Schola Europaea

Northern Sami language, ISO 639-1 code

Spaceship Earth

Somatic Experiencing, a form of psychological therapy

Special edition

Mercedes-Benz SE, automobile, see Mercedes-Benz W108

SE postcode area of London

Star Airlines, IATA airline designator

Standard error (statistics), standard deviation of a sample normalized by the square root of the sample size

Southeast, one of the four ordinal directions, in weather forecasting and geography

Se (kana) (せ and セ), one of the Japanese kana

Single-ended, signalling method used in the SCSI standard

Ferrocarriles Unidos del Sureste, AAR reporting mark

Macintosh SE "System Expansion", a personal computer manufactured by Apple

Manually Coded English or Siglish

Sweden, ISO country code