Rio Grande do Sul, a Brazilian state

Denver and Rio Grande Western Railroad, a defunct railroad in the United States

Rio Grande do Norte, a Brazilian state

Rio Grande, Rio Grande do Sul

Rio Grande Pickups, a brand of guitar guitar pickups

Rio Grande City, Texas, United States

Republic of the Rio Grande, a republic which lasted less than a year in 1840

Rio Grande County, Colorado, United States

Rio Grande (Jamaica), a major river of Portland Parish, Jamaica

Rio Grande (aka "Río Bravo"), a river to the Gulf of Mexico, forming part of the Mexico-United States border

Río Grande, Puerto Rico (United States)

Rio Grande (film), a western released in 1950

University of Rio Grande, in Rio Grande, Ohio

Rio Grande Games, a board games publisher

Rio Grand, a country music group

Rio Grande (Paraná), a tributary of the Paraná River, in Brazil

Río Grande, Tierra del Fuego

Rio Grande, Minas Gerais

Río Grande (Bolivia), a tributary of the Mamoré River

Sport Club Rio Grande, a Brazilian football club.

Río Grande (Lugo), a river in the province of Lugo, Spain

Río Grande de San Miguel, a river in El Salvador

Rio Grande, New Jersey, a town in the USA

Rio Grande, Ohio, a town in the USA

Río Grande (Argentina), a river of Mendoza Province, Argentina

Rio Grande (Panama), Coclé Province, Panama

Río Grande de Santiago, a river in Mexico (see Lerma River)

Rio Grande, a space battleship apeared in Legend of the Galactic Heroes