Earthquake, an occurrence of seismic "shaking" of the Earth.

Quake, a 1996 first-person shooter computer game by id Software and the first game in the Quake series

Quake (character), a superhero construction worker created by Jay Ward and used by Quaker Oats to advertise Quake cereal

Quake (series), the series of computer games as a whole

Quake (Transformers), a fictional Transformers character.

Quake (natural phenomenon), the "shaking" of planets and interstellar bodies in general.

Quake, along with Quisp, one of a pair of Quaker Oats sweetened cereals advertised together in the 60s