Robotic probe, a robot that uses onboard instruments to gather and relay a variety of telemetry to controllers from remote, hazardous or otherwise difficult to reach locations

Space probe, a robotic probe operating in space

Probe, a Star Trek novel

Langmuir probe, a device that uses electrodes inserted into plasma to measure electron temperature, electron density, and plasma potential

Probe (StarCraft), a robotic worker in the real-time strategy computer game StarCraft

Ford Probe, a car produced by the Ford Motor Company between 1989 and 1997 for European and North American markets

Test probe, a device used to test electronic equipment

Hybridization probe, a nucleic acid used for the detection of complementary nucleic acid sequences

A term used in numismatics for a pattern coin

Probe (parlor game), a discontinued card game produced by Parker Brothers

Atom probe, an atomic-resolution microscope

Probe Ministries, an evangelical Christian organization

Probe (Philippine TV series), a public affairs/documentary show aired on the Philippine TV network ABS-CBN

Probe card, an interface between an electronic test system and a semiconductor wafer

SS7 probe, a device that extracts SS7 signaling information from telecommunications networks

Probe Records, a record label

Probe Entertainment, a British videogame developer

Probe (1972 TV pilot), an American TV pilot movie for the science-fiction detective series Search

Probe (TV series), a 1988 TV series starring Parker Stevenson

Probe, the quarterly science fiction fanzine of Science Fiction South Africa

Proxy-based estimating, a procedure for estimating size and effort