Power station, a facility for the generation of electric power.

A brand of chocolate bar manufactured by Peter Paul

Powerhouse Museum, a science and technology museum in Sydney, Australia

Powerhouse (comics), the name of several fictional characters in the Marvel Comics Universe

Powerhouse, a large function centre overlooking Albert Park and Lake in Melbourne, Victoria, Australia, after which many local recreational clubs are named.

Powerhouse (Deep Purple album), a 1977 album by Deep Purple.

Powerhouse (TV series), a United States television series

Powerhouse (song), a composition by Raymond Scott featured in many Warner Bros. cartoons

Brisbane Powerhouse, a performing arts center in Brisbane, Queensland, Australia

Eric Clapton's Powerhouse, a short-lived 1960s blues band

Powerhouse (programming language), a 1980s programming language by Cognos Corporation

Powerhouse (band), the name of several dance music projects

The Power-House, a 1916 novel by John Buchan

Powerhouse (album), a 2005 album by Mustasch.

Powerhouse (video game), a 1995 computer game by Impressions Games, now part of Vivendi SA.

Dick Smith Powerhouse, a chain of large electronics stores operating in Australia and New Zealand.

Powerhouse (club), a Rock and Metal club in Shifnal, Shropshire.