Portal (video game), a first-person puzzle game produced by Valve Corporation

Web portal, a site that functions as a point of access to information on the Internet

Portal (TV series), a series about MMORPGs

Charles Portal, 1st Viscount Portal of Hungerford, British Marshal of the RAF and Chief of the Air Staff in World War II

Portal (band), an independent progressive metal band from Canada

Portal (comics), a Marvel comic character

Portal stones, a type of stone monument

Portal, North Dakota

Enterprise portal, a framework to provide a single point of access to a variety of information and tools

Portal (Magic: The Gathering), a set in the Magic: The Gathering card game

Portal, Georgia

Portal (interactive novel), an early interactive novel for personal computers

Portal Software, a company based in Cupertino, California

Antoine Portal, French anatomist, doctor and medical historian

Portal rendering, an optimization technique in 3D computer graphics

Portal frame, a construction method

Portal (architecture), a gate or door

Nicolas Portal, French professional road bicycle racer

Portal (UK band), an ambient/dreampop band from the UK

Portal (fiction), a magical or technological doorway that connects two distant locations

Portal venous system, an occurance where one capillary bed drains into another through veins

Michel Portal, French composer, saxophonist, and clarinetist

Hepatic portal vein, a vein that drains blood from the digestive system