A Journal of the Plague Year, a novel by Daniel Defoe

Black Death, also known as The Black Plague: the Eurasian pandemic thought to have been caused by bubonic plague, beginning in the 14th century with repeated outbreaks until the 18th century.

The Plague, a novel by Albert Camus

Septicemic plague and

Bubonic plague, a specific disease caused by Yersinia pestis. Bubonic is one manifestation;

Plagues of Egypt, the 10 calamities that God inflicted on Egypt in the book of Exodus

A pandemic caused by such a disease

List of historical plagues

Capacitor plague, a condition afflicting computer motherboards in which capacitors fail

The Plague (English punk rock band), an English band

The Plague, an episode of Father Ted

The Plague (band), a New Zealand band

The Plague (magazine), New York University's comedy magazine

The Plague (film), a 2006 horror film

Plagues (album) by The Devil Wears Prada

Any pestilence, a virulent and highly infectious disease

Any bubo-causing disease