John Peale Bishop (1892–1944), American poet and man of letters

Norman Vincent Peale (1898–1993), American christian preacher and author

Rembrandt Peale (1778–1860), American neoclassical painter, son of C. W. Peale

Peale House, the building housing the office of the President of La Salle University, Philadelphia, Pennsylvania, USA

Charles Willson Peale (1741–1827), American painter, soldier and naturalist

Peale's Dolphin, a dolphin found near the southern tip of South America

Titian Peale (1799–1885), American artist, naturalist, entomologist and photographer, son of C. W. Peale

Raphael Peale (1774–1825), American painter of still-life, son of C. W. Peale

Peale Museum, a museum of painting and natural history in Baltimore, Maryland, USA

Charles Peale Polk (1767–1822), American portrait painter

James Peale (1749–1831), American painter, best known for his miniature and still-life paintings, brother of C. W. Peale

Mount Peale, the highest peak in the Manti-La Sal National Forest, Utah, USA

Peale's Falcon, a subspecies of peregrine falcon

Stanton J. Peale, American astronomer, recipient of the James Craig Watson Medal

Peale's Free-tailed Bat, a bat of South and Central America