People's Republic of China, a country in East Asia

Planning Research Corporation, a think tank in the metropolitan Washington, D.C. area

.prc, the file extension of executables for Palm OS

Presbyterian Reformed Church

Procfs, short for process filesystem: a pseudo-filesystem which is used to access kernel information about processes on Unix-like computers

Protestant Reformed Churches in America, a Protestant denomination of 27 churches and over 7,000 members

Phase response curve showing biological response to light in animals

Communist Refoundation Party, an Italian reformed communist party

Peterborough Regional College

Regionalist Party of Cantabria, the second oldest political party in the Spanish Autonomous Community of Cantabria

Popular Resistance Committees, various Palestinian militant organizations which operates in the Gaza Strip

Professional Regulation Commission, an agency of the government of the Republic of the Philippines

Volunteer computing or Public Resource Computing, a type of distributed computing

the file format of Mobipocket, a type of e-book

Portable Radio, Communication, an example is the AN/PRC-77 Portable Transceiver

Producers Releasing Corporation, one of the larger Hollywood production conglomerates of Poverty Row of the late 30s-mid 40s

Postal Regulatory Commission, an independent regulatory agency

Palestine Red Crescent Society, a humanitarian organization

Ernest A. Love Field (IATA code: PRC), a public airport near Prescott, Arizona