Pirates of the Caribbean, a Walt Disney entertainment franchise

Potential Officers Course, a leadership evaluation programme in the Royal Marines.

The "Professional Officer Course", a part of the United States Air Force Reserve Officer Training Corps program

"Product of conception", a term for an embryo

Push to Talk over Cellular (PoC), a variant of Push to Talk (PTT)

Port of call, any port visited by a ship except that ship's home port

People of Color, a term for causes relating to black people, Latinos, Asians, Pacific Islanders, Native Americans, or any ethnic or racial group other than white Europeans

Proof of concept, a term used in system development to prove the viability of a potential system

POC is a three-letter acronym that can stand for:

Proto Oceanic (POc), the protolanguage ancestral to Oceanic languages

Prisoner of conscience, a term used by Amnesty International

Playboy on Campus, a marketing program by Playboy Enterprises

Philippine Olympic Committee, the National Olympic Committee of the Philippines