PLC plastic

Polish-Lithuanian Commonwealth (1569-1795), a federal monarchic republic formed by Poland and Lithuania

Power line communication, including broadband PLC modes

Parti Libéral du Canada, the French name of the Liberal Party of Canada

Public limited company, in UK or Ireland, is a type of limited company whose shares may be sold to the public

Programmable logic controller, a small special-purpose computer used to automate machines

Pymble Ladies' College, an independent girls' school in Sydney, Australia

Psycho le Cemu, a Japanese visual kei rock band

Program length commercial, or infomercial

Partido Liberal Constitucionalista, the Spanish name of the Constitutional Liberal Party of Nicaragua

Platoon Leaders Course, A single ten week, or two six week program that the Marines use for possible OCS candidates, which is undertaken during the summer for college students.

Platoon Leaders Class, the United States Marine Corps training program for Marine Officer Candidates

Palestinian Legislative Council, law-making body of the Palestinian Authority

Phonetic loan character, an etymologic category of Chinese characters

Pityriasis lichenoides chronica, the chronic version of the immune system disease Pityriasis lichenoides et varioliformis acuta

Phospholipase C, an enzyme which cleaves PI(4,5)P2 to form IP3 and diacylglycerol

Pigmy Love Circus, a Los Angeles based rock band.

Prague linguistic circle, an influential school of linguistic thought

Presbyterian Ladies' College, the name of several independent girls' schools in Australia

Packet Loss Concealment, a technique to mask the effects of missing packets in VoIP communications

Polymorphic Lambda Calculus, a typed lambda calculus with parametric polymorphism (also known as System F)