Orpheus, 1980s-era villain on the American soap opera Days of Our Lives

"The Lyre of Orpheus", song and album-disk by Nick Cave

Orpheus, a character from Cornelia Funke's novel Inkspell

Orpheus, American release of 1949 French film Orphée

Orphée, 1949 French film

Orfeu Negro, 1959 French-directed Brazilian film Black Orpheus

Orpheus, a song by The Mekons

"Orpheus" (role-playing game)

Orpheus (band)

Orpheus Chamber Orchestra

Krewe of Orpheus, a New Orleans Mardi Gras krewe.

Orpheus headphones, model by Sennheiser

The Lyre of Orpheus, novel

Orpheus Roye, professional football player

HMS Orpheus, any of several vessels

Orpheus Musical Theatre Society

Orpheus Music, a record label

Orpheus, a 1947 ballet by Igor Stravinsky

The Mask of Orpheus, a 1984 opera by Harrison Birtwistle

Orpheus (comics), a DC Comics character

Lyra Orpheus, a silver saint from the popular anime/manga, Saint Seiya

Doctor Byron Orpheus, a character on the animated series The Venture Bros.

"Orpheus" (Angel episode), an episode title and fictional mystical drug from the TV series Angel

Orpheus (Stargate SG-1), an episode of the television series Stargate SG-1

"Orpheus" (2004 single), song by Ash

In Warhammer 40,000, The Praetors of Orpheus is a Space Marine Chapter.

Orpheus (planet), alternate name for Theia (planet)

Bristol-Siddeley Orpheus, a turbojet engine.

Orpheus Gate, a pass in Antarctica