North & South, a 1946 poetry collection by Elizabeth Bishop

North and South (1855 novel), a novel by Elizabeth Gaskell

North and South (TV miniseries), a miniseries based on the novels

"North and South" is Cockney rhyming slang for the mouth.

North & South (computer game), a strategy title focusing on the American Civil War for the Amiga, DOS, the NES, the Atari ST, and the Commodore 64 systems

North & South were a late 1990s boyband who starred in the television series No Sweat.

North and South (2004 TV serial), a BBC TV adaptation of Gaskell's novel

North and South (novel), the first novel in the series

North and South Railway, a defunct American railroad.

North and South (trilogy), a series of novels by John Jakes

The North-south position, a ground grappling position.

North and South an album by Gerry Rafferty.

North & South (magazine), a New Zealand magazine.